RNA Homeostasis and Immunity

We are particularly interested in the roles of RNA homeostasis in innate immunity and inflammatory responses, with an emphasis on host recognition and regulation of viral RNAs during infection. Our research focuses on interferon-stimulated genes (ISGs), RNA sensing pathways, and the structural mechanisms underlying antiviral immune responses.

Through the study of key RNA-protein complexes and immune regulatory networks, we seek to understand how aberrant RNA homeostasis contributes to viral pathogenesis, inflammatory disorders, and autoimmune diseases, ultimately providing insights for RNA-targeted immunomodulatory therapies and antiviral drug development.